Conference Venue
Conference Office
E-mail: serge.mykita
Phone:
+33 (0)3 68 85 48 69
+33 (0)3 68 85 48 69
Address:
Serge MYKITA
UMR7242
Biotechnologie et Signalisation Cellulaire
300, Boulevard Sébastien Brant
67400 Illkirch
http://bsc.unistra.fr
Serge MYKITA
UMR7242
Biotechnologie et Signalisation Cellulaire
300, Boulevard Sébastien Brant
67400 Illkirch
Programme
- Programme - PDF for printing | Abstracts
- Sunday 22. 9. | Monday 23. 9. | Tuesday 24. 9. | List of posters
SUNDAY September 22nd |
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| 18:00 | Meeting point for participants from outside Strasbourg at the reception of "Centre Culturel Saint Thomas", 2 rue de la Carpe Haute, 67000, Strasbourg |
| 19:00 | Welcome dinner at the restaurant “Zuem Strissel”, 5 place de la Grande Boucherie, 67000 Strasbourg |
MONDAY September 23rd |
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| 8:30 | Conference place: Salle de la convivialité, Centre Culturel Saint Thomas, 2 rue de la Carpe Haute, 67000, Strasbourg. |
| 8:50 | Opening by the conference organizers – Mathieu WELLHOF (Attaché de cooperation scientifique et universitaire, French institute in Prague), Tomas ETRYCH and Jean-Luc GALZI |
| 1st section: Chemistry in the cell | |
| Chair: Tomáš Etrych | |
| 9:00 – 9:25 | Alain WAGNER, Biofunctional Chemistry Laboratory, UMR 7199, Faculty of Pharmacy, LabEx Medalis, 67400 Strasbourg-Illkirch, France Low Conversion Chemistry for Stoichiometric Bioconjugation |
| 9:25 – 9:50 | Milan VRABEL, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic Bioorthogonal Reactions of Heterodienes: Application in Bioimaging and Beyond |
| 9:50 – 10:15 | Katerina POLAKOVA, Regional Centre of Advanced Technologies and Materials, the Faculty of Science, Palacký University Olomouc, Czech Republic Carbon dots for biomedical applications |
| 10:15 – 10:40 | Jiri MISEK, Department of Organic Chemistry, Faculty of Science, Charles University, Prague, Czech Republic Chiral fluorescent probes for chemical biology and catalysis |
| 10:40 – 11:00 | Posters and coffee break |
| 2nd section: Drug delivery and vectors | |
| Chair: Jean-Luc GALZI | |
| 11:00 – 11:25 | Daniel SCHERMANN, CNRS UMR 8258 – Inserm U1267, Paris Descartes University – School of Pharmacy, Paris, France Optimized miniplasmid vectors for non-viral gene therapy |
| 11:25 – 11:50 | Tomas ETRYCH, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Hydrophilic and amphiphilic copolymers useable as efficient nanotherapeutics or diagnostics |
| 11:50 – 12:15 | Guy ZUBER, UMR 7242 Biotechnology & Cellular Signaling, CNRS-University of Strasbourg, France Tuning self-assembling polyplexes with an endosomal pH-sensitive disassembling ability favors intracytosolic delivery of oligonucleotides and proteins |
| 12:15 – 13:30 | Posters and lunch |
| 3rd section: Drug discovery and platforms | |
| Chair: Daniel SCHERMANN | |
| 13:30 – 13:55 | Radim NENCKA, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic Design of novel human neutral sphingomyelinase 2 inhibitors as potential therapeutics |
| 13:55 – 14:20 | Didier ROGNAN, Laboratoire d’Innovation Thérapeutique (LIT), UMR7200 CNRS-Université de Strasbourg, 67400 Illkirch, France Discovery of first-in-class extracellular FLT3 inhibitors by in silico and experimental high-throughput screening: From hits to a preclinical candidate |
| 14:20 – 14:45 | Jaroslav ROH, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic Structure-Activity Relationships of 3,5-Dinitrophenyl-Containing Heterocyclic Compounds as Selective Antitubercular Agents |
| 14:45 – 15:10 | Priscille BRODIN, Université Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 – UMR 8204 – CIIL - Center for Infection and Immunity of Lille, F-59000 Lille, France Phenotypic screenings for the identification of new drugs and new targets involved in host-mycobacteria interactions |
| 15:10 – 15:30 | Posters and coffee break |
| 4th section: Bio-imaging and theranostic | |
| Chair: Milada SIROVA | |
| 15:30 – 15:55 | Elodie BRETTON, ICube Laboratory, UMR CNRS 7357, University of Strasbourg, France MRI-guided Therapies in Interventional Radiology |
| 15:55 – 16:20 | Miroslav POPPER, Institute of Molecular and Translational Medicine, Palacky University Olomouc, Czech Republic Small animal imaging centre of the Institute of Molecular and Translational Medicine |
| 16:20 – 16:45 | Jean-Luc COLL, INSERM U1209/UGA/ CNRS UMR5309, Institut for Advanced Biosciences, La Tronche, France Optical guided theranostic approaches |
| 16:45 – 17:10 | Peter KESA, Center for Advanced Preclinical Imaging (CAPI), First Faculty of Medicine, Charles University, Prague, Czech Republic In vivo Photoacoustic Monitoring of the Biodistribution of Cyanine Dyes Doped HPMA in Healthy and Tumor Mice |
| 17:10 – 17:35 | Adam MODRY, Center for Advanced Preclinical Imaging (CAPI), First faculty of medicine, Charles University, Prague, Czech Republic PET imaging of mantle cell lymphoma |
| 17:35 | Posters and drink |
| 19:00 | Dinner at the restaurant "La Vignette", 29 Rue Mélanie, 67000 Strasbourg |
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TUESDAY September 24th |
|
| 5th section: Physiopathology and drug discovery | |
| Chair: Peter KESA | |
| 9:00 – 9:25 | Sylviane MULLER, School of Biotechnology, University of Strasbourg, France Mechanism-guided novel therapies for treating inflammatory diseases |
| 9:25 – 9:50 | Milada SIROVA, Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic Anti-cancer immune responses and targeted therapy based on polymer drug delivery systems |
| 9:50 – 10:15 | Frederic SIMONIN, UMR7242-BSC, CNRS, University of Strasbourg, 67400 Illkirch, France A bifunctional biased mu opioid agonist - neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects |
| 10:15 – 10:40 | Posters and coffee break |
| 6th section: Animal models, organoids | |
| Chair: Sylviane MULLER | |
| 10:40 – 11:05 | Vincent FLACHER, Laboratoire CNRS UPR3572 Immunology, Immunopathology and Therapeutic Chemistry (I2CT), Institut de Biologie Moléculaire et Cellulaire, Université de Strasbourg, Strasbourg, France An innervated, vascularized and immunocompetent human skin model to study cutaneous neuroimmune interactions |
| 11:05 – 11:30 | Helena FULKOVA, Institute of Animal Science and Institute of Experimental Medicine CAS, Prague, Czech Republic Nucleolus precursor bodies: Atypical organelles in atypical cells |
| 11:30 – 11:55 | Jocelyn LAPORTE, Translational Medicine Department, IGBMC, Illkirch, France Modulation of amphiphysin and dynamin rescues severe congenital myopathies |
| 12:00 – 13:15 | Posters and lunch |
| 7th section: Inflammation | |
| Chair: Jocelyn LAPORTE | |
| 13:15 – 13:40 | Veronique WITKO, Institut Cochin, Paris, France Modulation of cytosolic Proliferating Cell Nuclear Antigen (PCNA) in neutrophils to promote the resolution of inflammation |
| 13:40 – 14:05 | Eva KOZIOLOVA, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Polymer-based drug delivery systems for treatment and diagnosis of inflammatory diseases |
| 14:05 – 14:30 | Jean-Luc GALZI, UMR 7242 Biotechnology & Cellular Signaling, CNRS, School of Biotechnology, University of Strasbourg, 67400 Illkirch, France Dynamics of GPCR signaling and application to bioactive molecules discovery |
| 14:30 – 14:40 | Closing of the meeting by the conference organizers – Mathieu WELLHOFF (Attaché de cooperation scientifique et universitaire, French institute in Prague) and Jean-Luc GALZI |
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Presented posters |
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| 1. Igor DOVGAN, Biofunctional Chemistry, UMR 7199, Faculty of Pharmacy, LabEx Medalis, Strasbourg-Illkirch, France Automated one-to-one linkage of proteins and payload |
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| 2. Nadja GROYSBECK, UMR 7242 Biotechnology & Cellular Signaling, CNRS-University of Strasbourg, France Thiolate-specific conjugation of cetuximab and nanobody to circa 2 nm gold nanoparticles as novel approach for targeting and imaging |
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| 3. Marie-Louise JUNG, Prestwick Chemical, 67400 Strasbourg-Illkirch, France The Prestwick Chemical Library, a valuable tool for screening |
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| 4. Galina KARABANOVICH, Farmaceutical Faculty, Charles University, Hradec Kralove, Czech Republic Novel derivatives of dexrazoxane: synthesis and structure in vitro cardioprotective activity relationships study |
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| 5. Adela KRATOCHVILOVA, Institute of Animal Physiology and Genetics CAS, Laboratory of Odontogenesis and Osteogenesis, Brno, Czech Republic Inhibition of pro-apoptotic caspases in osteoblasts causes changes in expression of Ocn and Phex genes |
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| 6. Xavier LE GUEVEL, INSERM U1209/UGA/ CNRS UMR5309, Institut for Advanced Biosciences, La Tronche, France Development of gold nanoclusters for optical imaging in the shortwave infrared window |
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| 7. Alena LIBANSKA, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Delivery systems for treatment and diagnosis of inflammatory diseases |
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| 8. Quentin MULLER, Laboratoire CNRS UPR3572, Immunology, Immunopathology and Therapeutic Chemistry (I2CT), Institut de Biologie Moléculaire et Cellulaire, Université de Strasbourg, Strasbourg, France Innervated and Vascularized Immunocompetent Human Tissue Engineering Skin to the Study of Cutaneous Neuroinflammation |
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| 9. Raphaëlle QUILLET, UMR 7242 Biotechnology & Cellular Signaling, CNRS-University of Strasbourg, France The neuropeptide FF1 receptor/rfamide-related peptide 3 system modulates nociception, opioid analgesia, inflammatory pain and luteinizing hormone release in rodents |
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| 10. Sruthi Vijaya RETNAKUMAR, School of Biotechnology, University of Strasbourg, France Exploiting autophagy-lysosomal dysfunction as therapeutic target in inflammatory bowel diseases |
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| 11. Caroline ROQUES, UTCBS Unité des Technologies Chimiques et Biologiques pour la Santé, UMR CNRS 8258 / Inserm U1022, Faculté de Pharmacie de Paris, France Vectors for Molecular Imaging and Targeted Delivery |
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| 12. Roberto SILVA-ROJAS, Pathophysiology of Neuromuscular Diseases Team, Translational Medecine and Neurogenetics Department, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 67400 Illkirch-Graffenstaden, France Reversal of the cellular phenotype of tubular aggregate myopathy (TAM) using a pharmacological approach |
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