Programme
Plenary lectures
- Prof. Jindřich (Henry) Kopeček, University of Utah, USA
CROSSLINKING OF RECEPTORS AS A DESIGN PRINCIPLE FOR SMART NANOMEDICINES - Prof. Katharina Landfester, Max-Planck Institute for Polymer Research, Mainz, Germany
POLYMERIC NANOCAPSULES: ENCAPSULATING, CAMOUFLAGING, TRANSPORTING AND RELEASING DRUGS - Prof. San Hoa Thang, Monash University, Australia
RAFT: A PROCESS FOR MAKING BETTER POLYMERS
Invited lectures
- Dr. Tomáš Etrych, Institute of Macromolecular Chemistry, Czech Academy of Sciences
POLYMER-BASED NANOMEDICINES FOR TREATMENT OF AGGRESSIVE LYMPHOMAS - Prof. Jun Fang, Sojo University, Japan
IMPROVING THERAPEUTIC EFFECT OF NANOMEDICINE BY EPR ENHANCERS - Prof. Kui Luo, Sichuan University, PR of China
TUMOR MICROENVIRONMENT-RESPONSIVE DENDRITIC POLYMERS BASED NANO-PLATFORMS FOR DRUG DELIVERY - Prof. Robert Luxenhofer, Julius-Maximilians-Universität Würzburg, Germany
POLY(2-OXAZOLINE) BASED BIOINKS - Prof. Hiroshi Maeda, BioDynamics Research Foundation, Japan
A NEW DIMENSION OF BORONO NEUTRON CAPTURE THERAPY (BNCT) FOR SOLID TUMOR TREATMENT - Prof. Benjamin Nottelet, University of Montpellier I, France
DEGRADABLE STAR BLOCK COPOLYMERS AS HIGHLY VERSATILE ARCHITECTURES FOR BIOMEDICAL APPLICATIONS - Dr. Lutz Nuhn, Max Planck Institute for Polymer Research, Germany
UNFOLDING NANOGELS FOR LOCAL AND SYSTEMIC CANCER IMMUNOTHERAPY - Dr. Milada Šírová, Institute of Microbiology, Czech Academy of Sciences
ANTI-TUMOR IMMUNE RESPONSES IN THE TREATMENT OF EXPERIMENTAL TUMORS WITH POLYMER PRODRUGS - Prof. Ijeoma Uchegbu, University College London, UK
DIFFERENTIATED MEDICINES FROM POLYMERIC NANOPARTICLES
Programme
Registration and all lectures take place at the Institute of Macromolecular Chemistry.
23/6
Sunday
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16:00 ‒ 19:00 |
Registration and welcome buffet |
24/6
Monday
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9:00 ‒ 9:10 |
OPENING Jiří Kotek (Director of the Institute) |
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9:10 ‒ 9:15 |
International Union of Pure and Applied Chemistry Jan Merna (Representative of IUPAC) |
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LECTURE SESSION 1 |
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| Chaired by: Robert Luxenhofer (Germany) | |
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9:15 ‒ 9:55 |
Plenary lecture PL-01 San Hoa Thang (Australia) RAFT: A process for making better polymers |
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9:55 ‒ 10:20 |
Oral communication O-01 Helena Henke (Austria) Polyphosphazenes: A degradable platform for nanomedicine |
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10:20 ‒ 10:45 |
Oral communication O-02 Libor Kostka (Czech Republic) Novel water-soluble biodegradable star-like polymer therapeutics |
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10:45 ‒ 11:05 |
Coffee break |
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LECTURE SESSION 2 |
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| Chaired by: San Hoa Thang (Australia) | |
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11:05 ‒ 11:35 |
Invited lecture IL-01 Ijeoma F. Uchegbu (United Kingdom) Differentiated medicines from polymeric nanoparticles |
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11:35 ‒ 12:00 |
Oral communication O-03 Yiwen Pei (United Kingdom) PISA as a versatile tool for ‘smart’ nanoparticles: Synthesis and characterisation |
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12:00 – 12:25 |
Oral communication O-04 Nikita Sedush (Russian Federation) Linear and star-shaped amphiphilic lactide copolymers: Synthesis and applications for drug delivery |
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12:25 – 13:30 |
Lunch |
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LECTURE SESSION 3 |
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| Chaired by: Ijeoma F. Uchegbu (United Kingdom) | |
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13:30 ‒ 14:00 |
Invited lecture IL-02 Robert Luxenhofer (Germany) Poly(2-oxazoline) based bioinks |
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14:00 ‒ 14:25 |
Oral communication O-05 Wanlin Xu (Belgium) Erasable hydrogen-bonded multilayers for the biocompatible release of templated nanostructures |
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14:25 ‒ 14:50 |
Oral communication O-06 Peter Kasak (Qatar) Zwitterionic layer for long-term durability and impedimetric HER2 biosensing in human serum: Glycoprofiling as a new approach towards breast cancer diagnostics |
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14:50 ‒ 15:15 |
Oral communication O-07 Uliana Kostiv (Czech Republic) Colloidally stable polymer-coated upconversion nanoparticles for biomedicine |
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15:15 ‒ 15:45 |
Coffee break |
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LECTURE SESSION 4 |
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Chaired by: Petr Chytil (Czech Republic) |
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15:45 ‒ 16:10 |
Oral communication O-08 Jorge Leganés (Spain) Hydrophobic graphene-based hydrogel: A multi-stimuli responsive drug delivery system |
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16:10 ‒ 16:35 |
Oral communication O-09 Olga Janoušková (Czech Republic) Study of true morphological structure of macroporous hydrogel scaffolds using SEM and LSCM – impact on cell growth |
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16:35 ‒ 17:00 |
Oral communication O-10 Emmanuelle Marie (France) Mixed ad layers of PLL-based copolymers to dynamically control cell adhesion/migration |
25/6
Tuesday
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LECTURE SESSION 5 |
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| Chaired by: Benjamin Nottelet (France) | |
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8:30 ‒ 9:10 |
Plenary lecture PL-02 Katharina Landfester (Germany) Polymeric nanocapsules: Encapsulating, camouflaging, transporting and releasing drugs |
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9:40 ‒ 10:05 |
Oral communication O-11 Sabah Kasmi (Belgium) Carbonated hydroxypropyl(meth)acrylamides: A versatile strategy for generating polymers with LCST and UCST behaviour |
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10:05 ‒ 10:30 |
Oral communication O-12 Svenja Morsbach (Germany) Nanocarriers in blood plasma with elevated immunoglobulin levels: Pre-coating counteracts individual variations |
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10:30 ‒ 11:00 |
Coffee break |
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LECTURE SESSION 6 |
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| Chaired by: Katharina Landfester (Germany) | |
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11:00 ‒ 11:30 |
Invited lecture IL-03 Benjamin Nottelet (France) Degradable star block copolymers as highly versatile architectures for biomedical applications |
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11:30 ‒ 11:55 |
Oral Communication O-13 Jana De Vrieze (Belgium) Extremely efficient lymph node delivery by polymer-cholesterol conjugate carriers of small molecule TLR7/8 agonist |
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12:10 – 13:30 |
Lunch |
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LECTURE SESSION 7 |
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| Chaired by: Tomáš Etrych (Czech Republic) | |
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13:30 ‒ 14:00 |
Invited lecture IL-04 Hiroshi Maeda (Japan) A new dimension of borono neutron capture therapy (BNCT) for solid tumor treatment |
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14:00 ‒ 14:25 |
Oral communication O-15 Lucia Kleščíková (Slovakia) Multicomponent polyelectrolyte complex-based microcapsule for immunoprotection of transplanted pancreatic islets |
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14:25 ‒ 14:50 |
Oral communication O-16 Cornelia G. Palivan (Switzerland) BIO-synthetic nanocompartments with in vivo functionality as artificial organelles |
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14:50 ‒ 15:15 |
Oral communication O-17 Asya Ivanova Petkova (United Kingdom) Glycol chitosan nanoparticles as delivery vehicles for gene therapy in glioblastoma |
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15:15 ‒ 15:45 |
Coffee break |
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LECTURE SESSION 8 |
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Chaired by: Hiroshi Maeda (Japan) |
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15:45 ‒ 16:15 |
Oral Communication O-14 Eva Koziolová (Czech Republic) Polymer-based drug delivery systems for treatment and diagnosis of inflammatory diseases |
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16:15 ‒ 16:40 |
Oral communication O-18 Stepan Podzimek (Germany) Light scattering for structural studies of polymers used in medicine |
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16:40 ‒ 17:05 |
Oral communication O-19 Josef Chmelař (Czech Republic) Biodegradable free-standing films from lauroyl hyaluronan |
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17:05 ‒ 17:30 |
Oral communication O-20 Alexandra Van Driessche (Belgium) Development of stable doxorubicin nanoparticles exhibiting reduced systemic toxicity |
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17:30 ‒ 19:00 |
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26/6
Wednesday
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LECTURE SESSION 9 |
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| Chaired by: Kui Luo (People's Republic of China) | |
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9:00 ‒ 9:40 |
Plenary lecture PL-03 Jindřich Kopeček (USA) Crosslinking of receptors as a design principle for smart nanomedicines |
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9:40 ‒ 10:05 |
Oral communication O-21 Maria Cristina Cringoli (Italy) Irreversible photo-switch on self-assembling tripeptides |
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10:05 ‒ 10:30 |
Oral communication O-22 Carmen Scholz (USA) Poly(amino acid)s in biomedicine: From gene delivery to implant surface coatings |
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10:30 ‒ 11:00 |
Coffee break |
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LECTURE SESSION 10 |
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| Chaired by: Jindřich Kopeček (USA) | |
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11:00 ‒ 11:30 |
Invited lecture IL-06 Kui Luo (People's Republic of China) Tumor microenvironment-responsive dendritic polymers based nano-platforms for drug delivery |
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11:30 ‒ 11:55 |
Oral Communication O-23 Piotr Mazurek (Denmark) Glycerol-silicone elastomers as active matrices with controllable release profiles |
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11:55 – 12:20 |
Oral Communication O-24 Béla Iván (Hungary) Nanostructured macromolecular assemblies as controlled drug release carriers: From intelligent drug release to high efficiency drug solubilization with nanomicelles of self-assembling hyperbranched block copolymers |
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12:20 – 13:30 |
Lunch |
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14:00 ‒ 17:00 |
Social programme |
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19:00 ‒ 22:00 |
Conference dinner |
27/6
Thursday
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LECTURE SESSION 11 |
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| Chaired by: Lutz Nuhn (Germany) | |
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9:00 ‒ 9:30 |
Invited lecture IL-07 Jun Fang (Japan) Improving therapeutic effect of nanomedicine by EPR enhancers |
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9:30 ‒ 9:55 |
Oral communication O-25 Khaled Greish (Bahrain) The use of styrene maleic acid nanomicelles encapsulating the synthetic cannabinoid analog WIN55,212-2 for the treatment of triple negative breast cancer |
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9:55 ‒ 10:20 |
Oral communication O-26 Kinga Pielichowska (Poland) Polyurethanes modified with polysaccharides and magnetite for orthopedic application |
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10:20 ‒ 10:45 |
Coffee break |
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LECTURE SESSION 12 |
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| Chaired by: Jun Fang (Japan) | |
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10:45 ‒ 11:15 |
Invited lecture IL-08 Milada Šírová (Czech Republic) Anti-tumor immune responses in the treatment of experimental tumors with polymer prodrugs |
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11:15 ‒ 11:40 |
Oral Communication O-27 Tanja Thomsen (Switzerland) T-cell mediated drug delivery across the blood-brain barrier |
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11:40 – 12:05 |
Oral Communication O-28 Annemiek Uvyn (Belgium) Efficient innate immune killing of cancer cells triggered by cell surface anchoring of multivalent antibody recruiting polymers |
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12:05 – 13:10 |
Lunch |
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LECTURE SESSION 13 |
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| Chaired by: Milada Šírová (Czech Republic) | |
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13:10 ‒ 13:40 |
Invited lecture IL-09 Lutz Nuhn (Germany) Unfolding nanogels for local and systemic cancer immunotherapy |
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13:40 ‒ 14:05 |
Oral communication O-30 Robert Pola (Czech Republic) Peptide-targeted polymer probes used for fluorescence-guided endoscopic surgery |
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14:05 ‒ 14:30 |
Oral communication O-29 Igor Krupa (Qatar) Light driven polymer actuators for designing of tactile displays |
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14:30 ‒ 14:55 |
Oral communication O-31 Shrina Bhagat (United Kingdom) In-vitro dissolution of reverse enteric polymer coated multiparticulates using electrochemical and high-resolution mapping techniques |
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14:55 ‒ 15:25 |
Invited lecture IL-05
Polymer-based nanomedicines for treatment of aggressive lymphomas |
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15:25 ‒ 15:40 |
Closing of the Meeting, Farewell drink |
LIST OF POSTERS
| P-01 | R. O. Silva, J. Massa Ribeiro, D. B. Foguel, K. G. de Holanda E Silva, A. C. Silvino, K. Dahmouche (Brazil) Development of new Siloxane-PEO-PLA hybrid matrices for long-term release of Penicillin G |
| P-02 | L. J. C. Albuquerque, V. Sincari, A. Jäger, J. Kučka, E. Pavlova, P. Pouckova, J. Humajova, P. Štěpánek, F. C. Giacomelli, E. Jäger (Brazil) Stimuli-responsive polymersomes towards the intracellular delivery of doxorubicin |
| P-03 | N. Milošević, M. Ruetter, Y. Ventura, V. Feinshtein, A. David (Israel) Drug-free E-selectin-targeted therapeutic copolymer for the treatment of alcoholic liver disease (ALD) |
| P-04 | D. Niewolik, K. Jaszcz, B. Bednarczyk-Cwynar, P. Ruszkowski (Poland) Studies on the preparation of betulin based polyanhydrides for use in inhalation drug delivery systems |
| P-05 | G. Slor, R. J. Amir (Israel) Self-assembly of enzyme-responsive polymeric amphiphiles into micelles with different hydrophilic shells |
| P-06 | M. Szekalska, K. Winnicka (Poland) Effect of oligosaccharides addition on mechanical and mucoadhesive properties of alginate films with posaconazole |
| P-07 | M. Ayyoob, X. Yang, Y. J. Kim (Republic of Korea) Preparation and chracterization of biodegradable well-defined block copolysters of lactide and glycolide |
| P-08 | F. Adams, O. M. Merkel (Germany) Synthesis of spermine-based polyamines for nucleic-acid delivery |
| P-09 | A. Gupta, B. S. Kim (Republic of Korea) Development of toughened polycaprolactone based shape memory polyurethane chitosan biocomposites |
| P-10 | X. Yang, M. Ayyoob, Y. J. Kim (Republic of Korea) Synthesis and characterization of multiblock semi-crystalline hydrophobic poly(ether ketone)-partially fluorinated hydrophilic disulfonated poly(arylene ether sulfone) copolymers |
| P-11 | D. Oleshchuk, P. Šálek, J. Dvořáková, D. Babuka, E. Pavlova, J. Kučka, L. Šefc, V. Proks (Czech Republic) Effect of surfactants on biocompatible and biodegradable poly(N5-2-hydroxypropyl-L-glutamine)-based nanogel preparation and in vivo imaging of nanogel biodistribution |
| P-12 | M. Holubova, M. Rabyk, L. Loukotova, J. Hromadkova, M. Hruby, P. Stepanek (Czech Republic) Polymer promoters and inhibitors of amyloid fibrils formation |
| P-13 | J. Martiska, E. Snejdrova, S. Podzimek, M. Dittrich (Czech Republic) Branched PLGA derivatives as prospective drug carriers |
| P-14 | G. Li, S. He, D. T. Martin, A. G. Schatzlein, I. F. Uchegbu (United Kingdom) A novel lipid-polymer hybrid system for efficient yet biocompatible gene delivery |
| P-15 | V. Demina, N. G. Sedush, S. Krasheninnikov, S. Chvalun (Russian Federation) Biodegradable composite materials based on polylactide and calcium phosphates with advanced properties for orthopedics |
| P-16 | S. H. Lee, J. H. Lim, K. M. Kim (Republic of Korea) Fabrication of PVP/PVA hydrogels containing polyhedral oligomeric silsesquioxane (POSS) via electron beam irradiation |
| P-17 | V. Gomzyak, I. Gritskova, V. Zubov, S. Chvalun (Russian Federation) Biodegradable amphiphilic multi-arm block copolymers based on hyperbranched polyester 2,2-bis(methylol)propionic acid |
| P-18 | D. Treľová, L. Kleščíková, V. Raus, L. Uhelská, Z. Kroneková, A. Chovancová, J. Kronek, M. Pelach, F. Dorchei, A. Heydari, P. Rios, J. McGarrigle, Y. Wang, A. M. Rokstad, J. Oberholzer, I. Lacík (Slovakia) Multicomponent polyelectrolyte complex-based microcapsules: Correlation between the encapsulation conditions and microcapsule properties |
| P-19 | Y. Bernhard, R. Hoogenboom (Belgium) Poly(2-oxazoline) conjugate with salicylic acid via ester linkage for the slow release of a non-steroidal anti-inflammatory drug |
| P-20 | M. Y. Badr, N. S. Abdulrahman, A. G. Schatzlein, I. F. Uchegbu (United Kingdom) Polymeric aqueous (FK 506) for topical ocular delivery in rabbits |
| P-21 | C. Pinese, S. Jebors, T. Montheil, A. Bethry, S. Verquin, C. Dupont, A. Mehdi, J. Martinez, G. Subra (France) Turning peptide into bioactive nylon |
| P-22 | A. Braunová, P. Chytil, R. Laga, M. Šírová, D. Machová, J. Parnica, O. Janoušková, T. Etrych (Czech Republic) Micellar nanotherapeutics for treatment of solid tumours: A comparative study |
| P-23 | L. Kotrchová, L. Kostka, A. Libánská, V. Šubr, M. Šírová, T. Etrych (Czech Republic) Biodegradable polymer carriers for therapy and diagnostic of solid tumor |
| P-24 | J. Kudláčová, L. Kotrchová, M. Filipová, O. Janoušková, T. Etrych (Czech Republic) The synthesis of fluorescent HPMA copolymers and their penetration study to tumor spheroids |
| P-25 | M. Bláhová, E. Koziolová, L. Kotrchová, B. Nottelet, T. Etrych (Czech Republic) PCL-pHPMA graft copolymers for efficient drug delivery |
| P-26 | M. Pechar, R. Pola, S. K. Filippov, T. Etrych, V. Král, I. Sieglová, M. Fábry (Czech Republic) Polymer cancerostatics targeted to GD2–positive tumors via recombinant antibody fragments |
| P-27 | D. Machová, E. Koziolová, P. Chytil, K. Venclíková, T. Etrych, O. Janoušková (Czech Republic) Nanotherapeutics based on HPMA copolymer-bound ritonavir – detail in vitro characterization |
| P-28 | M. Nahorniak, V. Oleksa, V. Samaryk (Czech Republic) Polysaccharide-based nano- and microparticles prepared by steglich reaction |
| P-29 | A. Libánská, E. Koziolová, G. Renault, D. Scherman, T. Etrych (Czech Republic) Delivery systems for treatment and diagnosis of inflammatory diseases |
| P-30 | O. Lidický, D. Machová, M. Alam, L. Daumová, E. Pokorná, P. Klener, T. Etrych (Czech Republic) Targeted drug delivery systems for non-hodkgins lymphoma therapy |
| P-31 | M. R. Tavares, M. Šírová, K. Hrabánková, T. Etrych, P. Chytil (Czech Republic) HPMA polymer conjugates with cucurbitacin-D and doxorubicin intended for immuno-oncotherapy |
| P-32 | M. Kaňa, A. Braunová, T. Etrych, J. Bouček, M. Šírová (Czech Republic) Effect of physico-chemical characteristics of polymer micellar nanotherapeutics on their biological activity in treatment of chemoresistant tumors |
| P-33 | M. S. Haider, M. M. Lübtow, R. Luxenhofer (Germany) Think beyond the core: Investigating the role of hydrophilic corona on the drug loading capacity of polymer micelles |
| P-34 | J. Plchova, K. Venclíková, O. Janoušková, J. Hrabeta, T. Eckschlager, K. Kopeckova, Z. Hampejsova, Z. Bosakova, J. Sirc, R. Hobzova (Czech Republic) Polylactide/polyethylene glycol fibers as a drug carrier for local chemotherapy |
| P-35 | M. Filipová, E. Böhmová, R. Pola, M. Pechar, T. Etrych, O. Janoušková (Czech Republic) RGD-containing HPMA copolymer conjugates for targeting to alpha(V)beta(3) integrin |
