News archive

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Smart biosensors help detect inflammation early in patients with joint replacements

A team led by Elena Tomšík from the Department of Conducting Polymers at the IMC is developing smart biosensors with higher accuracy, smaller dimensions, and broader diagnostic capabilities based on specific inflammatory markers.

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Hydrophilic polymers as functional excipients in dermal nanoformulations of imiquimod

Together with colleagues from UCT, we tested our developed hydrophilic polymer carriers as functional excipients in dermal drug nanoformulations.

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Polyaniline-modified porous carbon electrodes for high-energy symmetric and Zn-ion supercapacitors

Scientist from IMC report polyaniline-modified biomass carbon electrodes delivering high-energy symmetric and zinc-ion hybrid supercapacitors via optimized electrochemical deposition methods.

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Effect of XPS analysis on the structure of polymer brushes

The journal Applied Surface Science published a study addressing the impact of XPS measurements on the structure of zwitterionic polymer brushes, along with recommendations for minimizing this effect.

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Morphology-tuned polymer–drug conjugates for adaptive therapy

Researchers at IMC CAS developed pH-responsive polymer–drug nanoconjugates with controlled morphology, improving adaptive delivery and anticancer efficacy.

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Solution behavior of HPMA polymers with different chain architectures

Polymer Chemistry (RSC) published a study on how polymer architecture affects the solution behavior of water-soluble polymers, important for developing new materials.

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Stimulus-responsive polymer systems for photodynamic therapy of solid tumors

ACS Omega journal published study on stimulus-responsive polymer systems intended for effective photodynamic therapy of solid tumors.

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Stabilized polypyrrole for long-life supercapacitors

The published study introduces a PPy/HPStDVB composite enabling exceptional electrochemical stability and long-term durability of polymer-based supercapacitors.

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Possible applications of anticancer peptide KLAK in tumor treatment

European Journal of Medicinal Chemistry published a review article on anticancer peptide KLAK, which disrupts the mitochondrial membrane, enabling programmed death of cancer cells.

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TYRAY-modified alginate bioinks for 3D printing and vascular network formation

The research team developed alginate bioinks modified with the biomimetic TYRAY peptide, enhancing adhesion, growth, and self-organization of stem and endothelial cells and enabling the formation of vascular networks in 3D bioprinted constructs.

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Morphologically diverse thermo- and pH-responsive nano-objects from polymerization-induced self-assembly

We demonstrate controlled formation of morphologically rich polymer nano-objects dual-responsive to temperature and pH via aqueous RAFT-PISA.

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Multifunctional polymethacrylamides via “click” chemistry

An IMC team reported a new pathway to useful substituted polymethacrylamides via a highly-efficient “click” chemistry on a poly(2-isopropenyl-2-oxazoline) derivative.

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Antibody-targeted polymeric nanomedicines for effective low-dose treatment of breast tumors

Scientists from the IMC in collaboration with French colleagues have developed a method for the synthesis of advanced nanotherapeutics that are suitable for highly effective treatment of breast tumors.

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Maleimide-pHPMA mucoadhesive polymer for nasal delivery

Non-toxic maleimide-functional pHPMA polymer can increase the absorption of low-molecular-weight drugs by the nasal mucosa, thereby prolonging their retention.

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Advanced characterisation of DOTA complexes in solution and solid state

Structure of three DOTA complexes was thoroughly studied by NMR spectroscopy and X-ray diffraction, including intermolecular interaction and solution dynamics.

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NMR crystallography of Hg(II) complexes and spin–orbit effects of heavy elements

The study reveals spin–orbit coupling effects on NMR parameters of Hg(II) complexes using combined NMR crystallography and computational chemistry.

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Advanced erbium-polyaniline QD composites for next-generation energy storage

Scientists from IMC have synthesized PANI quantum dots for the first time. The journal Nanoscale published a study on the significant improvement of the electrochemical performance of Er-PANI-QDs under the influence of light.

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Synthesis, luminescence and cell interactions of ultrasmall upconversion nanoparticles

Original ultrasmall light-upconverting nanoparticles circulating in body undetected by immune system and being easily excreted were developed at IMC.

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Jiří Brus awarded the Doctor of Sciences (DSc.) degree

Jiří Brus received the DSc. diploma at a ceremonial event from Radomír Pánek, President of the Czech Academy of Sciences.

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Stabilizer-guided engineering of polypyrrole colloids for bioelectronic applications

Polypyrrole-based colloids, stabilized by various agents, offer tunable physicochemical and biological properties for advanced bioelectronic and energy storage applications.