News archive

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Stimulus-responsive polymer systems for photodynamic therapy of solid tumors

ACS Omega journal published study on stimulus-responsive polymer systems intended for effective photodynamic therapy of solid tumors.

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Stabilized polypyrrole for long-life supercapacitors

The published study introduces a PPy/HPStDVB composite enabling exceptional electrochemical stability and long-term durability of polymer-based supercapacitors.

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Possible applications of anticancer peptide KLAK in tumor treatment

European Journal of Medicinal Chemistry published a review article on anticancer peptide KLAK, which disrupts the mitochondrial membrane, enabling programmed death of cancer cells.

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TYRAY-modified alginate bioinks for 3D printing and vascular network formation

The research team developed alginate bioinks modified with the biomimetic TYRAY peptide, enhancing adhesion, growth, and self-organization of stem and endothelial cells and enabling the formation of vascular networks in 3D bioprinted constructs.

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Morphologically diverse thermo- and pH-responsive nano-objects from polymerization-induced self-assembly

We demonstrate controlled formation of morphologically rich polymer nano-objects dual-responsive to temperature and pH via aqueous RAFT-PISA.

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Multifunctional polymethacrylamides via “click” chemistry

An IMC team reported a new pathway to useful substituted polymethacrylamides via a highly-efficient “click” chemistry on a poly(2-isopropenyl-2-oxazoline) derivative.

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Antibody-targeted polymeric nanomedicines for effective low-dose treatment of breast tumors

Scientists from the IMC in collaboration with French colleagues have developed a method for the synthesis of advanced nanotherapeutics that are suitable for highly effective treatment of breast tumors.

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Maleimide-pHPMA mucoadhesive polymer for nasal delivery

Non-toxic maleimide-functional pHPMA polymer can increase the absorption of low-molecular-weight drugs by the nasal mucosa, thereby prolonging their retention.

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Advanced characterisation of DOTA complexes in solution and solid state

Structure of three DOTA complexes was thoroughly studied by NMR spectroscopy and X-ray diffraction, including intermolecular interaction and solution dynamics.

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NMR crystallography of Hg(II) complexes and spin–orbit effects of heavy elements

The study reveals spin–orbit coupling effects on NMR parameters of Hg(II) complexes using combined NMR crystallography and computational chemistry.

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Advanced erbium-polyaniline QD composites for next-generation energy storage

Scientists from IMC have synthesized PANI quantum dots for the first time. The journal Nanoscale published a study on the significant improvement of the electrochemical performance of Er-PANI-QDs under the influence of light.

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Synthesis, luminescence and cell interactions of ultrasmall upconversion nanoparticles

Original ultrasmall light-upconverting nanoparticles circulating in body undetected by immune system and being easily excreted were developed at IMC.

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Jiří Brus awarded the Doctor of Sciences (DSc.) degree

Jiří Brus received the DSc. diploma at a ceremonial event from Radomír Pánek, President of the Czech Academy of Sciences.

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Stabilizer-guided engineering of polypyrrole colloids for bioelectronic applications

Polypyrrole-based colloids, stabilized by various agents, offer tunable physicochemical and biological properties for advanced bioelectronic and energy storage applications.

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Sulfated glycogen: A natural polysaccharide-based trap for proinflammatory peptides

We developed sulfated glycogen that sequesters cationic peptides and reduces melittin-caused toxicity as potential psoriasis therapeutic.

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Memorial hall of isotactic polypropylene

The article introduces scientists and key discoveries related to the synthesis and structural development of an important polymer.

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Hidden architecture of alginate paramagnetic networks revealed by ss-NMR

We revealed nanoscale structures of copper- and iron-crosslinked alginates using advanced ss-NMR, unlocking biomedical and energy applications.

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Three patents of the Institute of Macromolecular Chemistry, Czech Academy of Sciences, have potential applications in medicine

Three high-level research results of the IMC CAS have been patented in the past six months. Obtaining a patent is a demanding process, but also a confirmation that the outcome is truly innovative and has real potential for industrial application.

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Polypyrrole-coated thermally activated carbon cloth for high-performing solid-state supercapacitors

Scientists from IMC, in collaboration with the University of Groningen, have engineered novel oCVD-synthesized polypyrrole electrodes on thermally activated carbon cloth, enabling high-performance symmetric and asymmetric supercapacitors.

Ostatní

Thermo- and ROS-responsive triblock copolymers for 19F magnetic resonance imaging

Scientists from IMC contributed to developing contrast agents for ^19F magnetic resonance imaging that are sensitive to temperature changes and reactive oxygen species (ROS).