||The project is aimed at identifying new applications of copper-catalyzed reversible-deactivation radical polymerization (Cu-RDRP) in polymer synthesis. The first goal is to find conditions for controlled Cu-RDRP of monomers that have not been previously polymerized by this technique, or the previous attempts did not bring satisfactory results. In this regard, special attention will be paid to polar and water-soluble monomers. The second goal of the project is the search for new types of initiators, particularly chlorinated ones, that may find use especially in aqueous Cu-RDRP. Besides the influence the initiator has on the polymerization course, the possibilities of easier attachment of the initiation groups onto various substrates will be investigated. The optimized polymerization protocols will be used for the preparation of new types of amphiphilic copolymers, and the solution properties of these polymeric materials will be studied in cooperation with the Faculty of Science, Charles University.