Nanoparticles from the IMC could help to better diagnose serious diseases

A multidisciplinary team of scientists has developed a new diagnostic methodology using photon-converting nanoparticles to prepare special markers for more accurate and faster detection of biomarkers for various diseases, including cancer. The method allows for early detection of disease or mild deterioration of health in the early stages. Scientists from the Department of Polymer Particles of the Institute of Macromolecular Chemistry also participated in the development of the nanoparticles. The results of the research have now been published in the prestigious journal Nature Protocols.

Scientists working largely in the Czech Republic have developed a new diagnostic methodology using photon-converting nanoparticles to prepare special markers for the accurate and rapid detection of biomarkers, particularly cancer biomarkers. The method allows for early detection of disease, as well as to help doctors diagnose even mild deterioration in the early stages of the disease. The multidisciplinary team consisted of scientists from the Institute of Analytical Chemistry of the CAS, the CEITEC research centre of Masaryk University (MU), the Faculty of Science of MU, the Institute of Macromolecular Chemistry of the CAS, the German University of Regensburg and the Swedish company Lumito AB.

"We met our colleagues from the University of Regensburg and Masaryk University during scientific meetings of COST Action CM1403: The European upconversion network –⁠ from the design of photonupconverting nanomaterials to biomedical applications", recalls Dr. Daniel Horák, Head of the Department of Polymer Particles of the Institute of Macromolecular Chemistry of the CAS. "Now our collaboration has resulted in several publications, published e.g. in Biomolecules and Nature Protocols", adds Dr. Horák.

 

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