News archive

Scientists from IMC revealed the tunable affinity of block polyoxazolines to cytoplasm membranes, based on their hydrophobicity

A study describing new polymeric theranostics whose photodynamic antitumor effect and fluorescence imaging of tumor tissue is activated by the tumor stimulus was published in the journal Theranostics.

Scientists from IMC participated in a study revealing the ability of meta-isobutoxy phenylboronic acid to create biocompatible hydrogels with multi-responsive properties.

The anchoring of ionic liquids into the structure of layered double hydroxides leads to the preparation of an efficient heterogeneous catalyst for microwave polymerization.

A study on monitoring the drug release kinetics using alternative methods, specifically surface plasmon resonance, capillary electrophoresis and nuclear magnetic spectroscopy, was published in the Communication Chemistry journal.

Comparison of the antifouling properties of poly(2-oxazoline) and poly(2-oxazine) polymer brushes, emerging alternatives to PEG, was published in Macromolecular Rapid Communications.

Within an international collaboration, IMC scientists developed new, low pH- and Mg²⁺ ions-tolerant copolymers aimed at the isolation and study of membrane proteins.

Gradient copolymers of hydrophilic and hydrophobic 2-oxazolines effectively inhibit amyloid fibril formation in a concentration-dependent manner, offering promise for treating amyloidoses.

In Polymers was published a study highlighting effect of amines on surface of chitin nanowhiskers on performance of polycaprolactone/polylactide biocomposites.

Within the national collaboration of IMC-UTB, conducting spherical PEDOT with improved antibacterial properties was prepared and possess diverse spectrum of applications, including optical sensors and medical devices.

An article describing the synthesis of Ceramide NP grafted to hyaluronan, a promising molecule for the treatment of inflammatory skin diseases, was published in Carbohydrate polymers.

Team Polymer and Colloidal Immunotherapeutics developed an efficient method for anchoring synthetic polymers to the surface of magnetic nanoparticles. The effectiveness of this surface treatment was subsequently assessed in vivo in collaboration with CAPI team from the 1st Faculty of Medicine.

In the framework of the European project NEWELY, the scientific team of IMC and UCT has developed homogeneous ion-exchange membranes with low surface resistance for highly efficient membrane-based alkaline electrolysis of water. The project was awarded the "Best Innovation Award 2022“ of the Clean Hydrogen Partnership at the European Hydrogen Week 2022 - "The secret to success is in the membrane".

A Czech-French research team has developed an anti-tumor micellar drug delivery system with ultrasound-triggered drug release and successfully tested it in a mousebrain tumor - glioma model. The biodistribution of the system within the organism and its accumulation in tumor can be monitored in real time as a direct feedback by PET or fluorescence.

Scientists from the IMC prepared fluorescent polymer probes designed for fluorescent guided surgery, which can light up tumors and more accurately showed tumor borders for easier resection of the whole tumor.

Scientist from the IMC developed a novel polypyrrole-based adsorbent of Cr(VI) ions with good handling properties for water purifications.

IMC scientists designed two-color optical contrast agent with reduced degradability under physiological conditions that is suitable for in vitro and in vivo imaging.

As part of the Czech-German-Japanese collaboration, scientists from the IMC participated in the study of changes in illumination intensity in the kinetics of the singlet oxygen signal and photosensitizer phosphorescence in vivo, using time-resolved optical detection in the NIR.

In the journal Nanomaterials, an article revealing the influence of electron-donor units on the formation of silver nanoparticles on the surface of thin layers of donor-acceptor copolymers was published.

He received the title of professor on the proposal of the Scientific Council of Charles University for the field of macromolecular chemistry.