News archive

IMC scientists designed two-color optical contrast agent with reduced degradability under physiological conditions that is suitable for in vitro and in vivo imaging.

As part of the Czech-German-Japanese collaboration, scientists from the IMC participated in the study of changes in illumination intensity in the kinetics of the singlet oxygen signal and photosensitizer phosphorescence in vivo, using time-resolved optical detection in the NIR.

In the journal Nanomaterials, an article revealing the influence of electron-donor units on the formation of silver nanoparticles on the surface of thin layers of donor-acceptor copolymers was published.

He received the title of professor on the proposal of the Scientific Council of Charles University for the field of macromolecular chemistry.

The OW Prize is awarded to selected, exceptionally high-quality young researchers of the CAS under the age of 35.

Within an international collaboration, IMC scientists participated in a study on the modeling of acrylic acid, methyl acrylate, and t-butylacrylamide copolymerization with the aim to optimize the industrial synthesis of multifunctional copolymers used in personal care products.

Within the international cooperation of IMC-UFABC, a paper focused on the influence of the permeability of polymersomes membranes on the release of encapsulated drug was published in Biomacromolecules.

In ACS OMEGA, IMC researches presented a versatile platform for the synthesis of pH-responsive diblock copolymer (PHPMA-b-PDPA) micelles and vesicles (polymersomes) obtained via microwave-assisted RAFT-PISA which may attract considerable attention in the drug-delivery field.

Journal ACS Applied Materials & Interfaces published a paper about influence of Zr-based metal-organic framework structure on properties of its composites with polyaniline.

First step of future investigations on dielectric properties of geopolymer for sensing applications in the field of building materials - international collaboration results were published in Materials and Structures.

The journal Pharmaceutics published a paper on nanofibrous drug carriers with prolonged release and biological activity against cancer cells with potential for local treatment of e.g. intraocular tumor retinoblastoma.

IMC scientists designed new Rose Bengal-conjugated and PEG-coated hexagonal upconverting nanoparticles to kill tumor cells by photodynamic therapy.

The journal Cell Transplantation has published results of in-vivo study of the survival, differentiation, and safety/tumorigenicity of reprogrammed human induced pluripotent stem cells-derived neuronal precursors for treatment of neurodegenerative diseases.

In research sponsored by the U.S. company Axalta Coating Systems, IMC scientists described the synthesis of well-defined low-molecular weight (co)polymers of glycidyl methacrylate applicable in the formulation of automotive coating mixtures.

Journal Solid State Ionics published work on the development of electrochemically, mechanically and thermally stable, efficient and versatile “green” gel polymer electrolytes for lithium-ion batteries based on cross-linked 2-polyoxazolines.

Researchers from IMC substantially contributed to the characterization of nanoparticles, which exhibit promising therapeutic properties for the treatment of Hungtington disease - a neurodegenerative disease of brain.

Interesting research published in Pharmaceutics manufactured novel amphiphilic, biocompatible and thermo-responsive PLA-b-PTEGMA copolymers synthesized via one-pot controlled RAFT-ROP polymerizations with fine-tuneable LCST. NPs prepared from them encapsulated and release paclitaxel by temperature-triggered drug release mechanism in relevant pathophysiological temperatures.

IMC scientists developed a method using electron beam irradiation to create nonbiofouling hydrogel coatings on implantable materials, improving biocompatibility and in vivo performance. Crosslinkable double bond concentration in the copolymer is crucial for stability and uniformity of the formed hydrogel layer.

We are deeply saddened to announce that on April 7th 2023, the physical chemist and leading expert in polymer chemistry Prof. Ing. Pavel Kratochvíl, DrSc. passed away.

A study was published in Materials, comparing the above characterizations on hydrogen-bond-rich rubbery elasto-plastic nanocomposites containing a monodisperse spherical rigid filler.