News archive

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Maleimide-pHPMA mucoadhesive polymer for nasal delivery

Non-toxic maleimide-functional pHPMA polymer can increase the absorption of low-molecular-weight drugs by the nasal mucosa, thereby prolonging their retention.

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Advanced characterisation of DOTA complexes in solution and solid state

Structure of three DOTA complexes was thoroughly studied by NMR spectroscopy and X-ray diffraction, including intermolecular interaction and solution dynamics.

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NMR crystallography of Hg(II) complexes and spin–orbit effects of heavy elements

The study reveals spin–orbit coupling effects on NMR parameters of Hg(II) complexes using combined NMR crystallography and computational chemistry.

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Advanced erbium-polyaniline QD composites for next-generation energy storage

Scientists from IMC have synthesized PANI quantum dots for the first time. The journal Nanoscale published a study on the significant improvement of the electrochemical performance of Er-PANI-QDs under the influence of light.

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Synthesis, luminescence and cell interactions of ultrasmall upconversion nanoparticles

Original ultrasmall light-upconverting nanoparticles circulating in body undetected by immune system and being easily excreted were developed at IMC.

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Jiří Brus awarded the Doctor of Sciences (DSc.) degree

Jiří Brus received the DSc. diploma at a ceremonial event from Radomír Pánek, President of the Czech Academy of Sciences.

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Stabilizer-guided engineering of polypyrrole colloids for bioelectronic applications

Polypyrrole-based colloids, stabilized by various agents, offer tunable physicochemical and biological properties for advanced bioelectronic and energy storage applications.

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Sulfated glycogen: A natural polysaccharide-based trap for proinflammatory peptides

We developed sulfated glycogen that sequesters cationic peptides and reduces melittin-caused toxicity as potential psoriasis therapeutic.

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Memorial hall of isotactic polypropylene

The article introduces scientists and key discoveries related to the synthesis and structural development of an important polymer.

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Hidden architecture of alginate paramagnetic networks revealed by ss-NMR

We revealed nanoscale structures of copper- and iron-crosslinked alginates using advanced ss-NMR, unlocking biomedical and energy applications.

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Three patents of the Institute of Macromolecular Chemistry, Czech Academy of Sciences, have potential applications in medicine

Three high-level research results of the IMC CAS have been patented in the past six months. Obtaining a patent is a demanding process, but also a confirmation that the outcome is truly innovative and has real potential for industrial application.

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Polypyrrole-coated thermally activated carbon cloth for high-performing solid-state supercapacitors

Scientists from IMC, in collaboration with the University of Groningen, have engineered novel oCVD-synthesized polypyrrole electrodes on thermally activated carbon cloth, enabling high-performance symmetric and asymmetric supercapacitors.

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Thermo- and ROS-responsive triblock copolymers for 19F magnetic resonance imaging

Scientists from IMC contributed to developing contrast agents for ^19F magnetic resonance imaging that are sensitive to temperature changes and reactive oxygen species (ROS).

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Radiopaque iodinated copolymers for image-guided drug delivery

The IMC scientists developed and published in the Nanoscale journal the CT-visible iodinated copolymers for image-guided drug delivery.

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Membranes for microdialysis of clinical samples

We have learned to produce ultrafiltration membranes in the form of miniature probes. We are able to modify their surface to improve biocompatibility without compromising separation efficiency.

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Effect of quaternized dextran charge density on the formation and properties of LbL films with heparin

The IMC team reported that polycation charge density significantly affects the formation and properties of quaternized dextran/heparin LbL films as potential biomaterial coatings.

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Magnetic polycaprolactone-based mats for bone tissue regeneration and cancer therapy

ACS Biomaterials Science and Engineering published study of IMC researchers on antibacterial and anticancer activity of tannic acid-modified polycaprolactone scaffolds.

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Biomass carbon sheets and polypyrrole synergize to improve supercapacitors performance

Scientists from IMC transformed the cinnamon biomass into carbon sheets and improved its electrochemical performance by preparing its composites with polypyrrole.

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Nanomaterials for diabetes: Targeted diagnostics and therapy

Scientists at IMC have developed smart upconversion nanoparticles for future diabetes theranostics allowing simultaneous targeted diagnostics and therapy.

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Biomass-sourced hydrogels for water purification

Researchers from the IMC contributed to the development of a hydrogel-based bioadsorbent for removing pesticides and dyes from wastewater.