Jiří Dybal, PhD
TopicStudy of the association mechanisms in thermosensitive polymers by the methods of Raman and infrared spectroscopy
AnnotationPluronics (poloxamers) are a group of non-ionic macromolecular surfactants and they are tri-block copolymers of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide), which are used in drug delivery, emulsification, detergency and in many other applications. Pluronics are also thermoresponsive: They are soluble in aqueous media at low temperatures, but with the increase of temperature above certain critical temperature, desolvation of the macromolecular chain takes place. The desolvation results in the formation of micelles, which are thermodynamically stable polymolecular aggregates. Some Pluronics can, in more concentrated aqueous solutions, transform from viscous solution into firm gel. Pluronic solutions can be combined with cellulose derivates in order to optimize the gelation process or to prepare materials with novel properties. These systems will be studied by the means of vibrational (infrared and Raman) spectroscopy and, as the case maybe, by computational (quantum mechanical) methods.

Otto Wichterle Centre of Polymer Materials and Technologies - CPMTOW

Centre of Biomedicinal Polymers - CBMP

Centre of Polymer Sensors - CPS

Polymers for Power Engineering - Energolab


Institute of Macromolecular Chemistry AS CR
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162 06 Prague 6
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