| Description |
Polysaccharides are essential biomacromolecules that have important biological functions in all living forms. Their wide range of pharmacological activities (anticancer, antimicrobial, antioxidant, antiviral or hypoglycemic) make them one of the most promising candidates in the biomedical and pharmaceutical fields. A key property enabling their diverse applications is the ability of polysaccharides to respond to physical stimuli and their willingness to undergo chemical and structural transformations leading to desired properties. The priority of therapeutic requirements in pharmaceutical technology is the targeted preparation of dosage forms with controlled physicochemical properties in terms of site of delivery and drug release rate. The aim is to create new intelligent drug carriers using the pharmacological activities of polysaccharides combined with their ability to respond to external stimuli and change their internal structure. The intention of this PhD project is to find, understand and define, through detailed structural analysis, the relationships of self-organization processes in drug-polysaccharide systems that lead to pharmaceutically desirable activity. |
