| Supervisor (Consultant) | Jiří Dybal, PhD |
|---|---|
| Topic | Study of the association mechanisms in thermosensitive polymers by the methods of Raman and infrared spectroscopy |
| Annotation | Pluronics (poloxamers) are a group of non-ionic macromolecular surfactants and they are tri-block copolymers of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide), which are used in drug delivery, emulsification, detergency and in many other applications. Pluronics are also thermoresponsive: They are soluble in aqueous media at low temperatures, but with the increase of temperature above certain critical temperature, desolvation of the macromolecular chain takes place. The desolvation results in the formation of micelles, which are thermodynamically stable polymolecular aggregates. Some Pluronics can, in more concentrated aqueous solutions, transform from viscous solution into firm gel. Pluronic solutions can be combined with cellulose derivates in order to optimize the gelation process or to prepare materials with novel properties. These systems will be studied by the means of vibrational (infrared and Raman) spectroscopy and, as the case maybe, by computational (quantum mechanical) methods. |
Center BIOPOL
Center BIOpolymer POstdoctoral Laboratory and educational center arises with finantial support from EU funds, operational programme Education for Competitiveness
Institute of Macromolecular Chemistry AS CR, v.v.i.
Heyrovského nám. 2
CZ-162 06 Praha 6
Czech Republic
phone:+420 296 809 111
fax:+420 296 809 410
