Supervisor
(Consultant)
MS.Daniel Horák, PhD.
TopicMagnetic nanoparticles with antibacterial properties: Synthesis, characterization and biological applications
AnnotationAntibacterial agents are recently important for disinfections and treatment of infectious diseases in medicine. However, they are toxic and bacteria are becoming resistant due to overprescription of antibiotics. The problem can be solved by metallic nanoparticles with strong antibacterial properties, such as Ag, which can be prepared by reductive methods. It is important to anchor or encapsulate Ag nanoparticles in a carrier to make them insoluble and colloidally stable, retain their properties and high surface area available for interactions with molecules. Last but not least, it is also necessary to easily manipulate, target, and separate the particles from liquid media. It follows from this a need to develop magnetic carriers. Aim of this work is to prepare superparamagnetic iron oxide nanoparticles with surface silver coatings with antibacterial properties. Physico-chemical and antibacterial properties of the nanoparticles will be evaluated and synthetic conditions controlled by selection of the reaction parameters will be correlated with properties of the particles. Nanoparticles with the surface shell exhibiting a maximal antibacterial activity will be offered for commercialization.

BIOpolymer POstdoctoral Laboratory and educational center - BIOPOL

Otto Wichterle Centre of Polymer Materials and Technologies - CPMTOW

Centre of Biomedicinal Polymers - CBMP

Centre of Polymer Sensors - CPS

Polymers for Power Engineering - Energolab


 

Institute of Macromolecular Chemistry AS CR, v.v.i.
Heyrovského nám. 2
CZ-162 06 Praha 6
Czech Republic
phone:+420 296 809 111
fax:+420 296 809 410

Strategie 21