Jakub Širc, PhD.
TopicIncorporation and controlled release of pharmacologically active compounds from hydrogel and nanofibrous polymer carriers
AnnotationThe PhD thesis will deal with the incorporation of biologically and pharmacologically active compounds to the polymer carriers and their consequent controlled release. The polymer carriers can be a) materials which primary function is the controlled delivery of a drug (e.g. a hydrogel carrier for controlled release in the gastrointestinal tract, nanofibers for local administration of anticancer drugs), b) materials with a different function and drug release increases significantly its therapeutic efficacy (e.g. hydrogel wound dressings, macroporous hydrogel scaffolds, tissue expanders). The research will be focused on the preparation of the polymer carriers and investigation of the effects influencing the release of the incorporated molecules according to the particular medicinal requirements. This PhD topic lies on the border of macromolecular, organic, physical and analytical chemistry. The research will be solved in cooperation with Czech and foreign collaborating institutions.
UniversitiesVysoká škola chemicko technologická v Praze, Přírodovědecká fakulta UK

Otto Wichterle Centre of Polymer Materials and Technologies - CPMTOW

Centre of Biomedicinal Polymers - CBMP

Centre of Polymer Sensors - CPS

Polymers for Power Engineering - Energolab


Institute of Macromolecular Chemistry AS CR
Heyrovského nám. 2
162 06 Prague 6
Czech Republic
tel:+420 296 809 111
fax:+420 296 809 410

Strategie 21