Jakub Širc, PhD.
TopicIncorporation and controlled release of pharmacologically active compounds from hydrogel and nanofibrous polymer carriers
AnnotationThe PhD thesis will deal with the incorporation of biologically and pharmacologically active compounds to the polymer carriers and their consequent controlled release. The polymer carriers can be a) materials whose primary function is the controlled delivery of a drug (e.g. a hydrogel carrier for controlled release in the gastrointestinal tract, nanofibers for local administration of anticancer drugs), b) have a different function and drug release increases significantly its therapeutic efficacy (e.g. hydrogel wound dressings, macroporous hydrogel scaffolds, tissue expanders). The research will be focused generally on the effects influencing the release kinetics and also on the preparation of the polymer carriers according to the particular medicinal requirements. PhD thesis lies on the border of macromolecular, organic, physical and analytical chemistry. The research will be carried in cooperation with Czech and foreign collaborating institutions.

BIOpolymer POstdoctoral Laboratory and educational center - BIOPOL

Otto Wichterle Centre of Polymer Materials and Technologies - CPMTOW

Centre of Biomedicinal Polymers - CBMP

Centre of Polymer Sensors - CPS

Polymers for Power Engineering - Energolab


Institute of Macromolecular Chemistry AS CR, v.v.i.
Heyrovského nám. 2
CZ-162 06 Praha 6
Czech Republic
phone:+420 296 809 111
fax:+420 296 809 410

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