Laboratory of Nanomaterials for Diagnostics and Biotechnology Processes

Research People Equipment Publications

(under BIOCEV program 4.1.2. Materials for Diagnostics and Biotechnological Processes)

(Head Ing. Michal Babič, PhD.)


Keywords: magnetic, polymer, nanoparticles, microparticles, ligands, diagnostics

Research areas

  • Synthesis, modification, characterisation, biomedical and biotechnological applications of polymer and composite nano- and microparticles

Main objectives

  • To increase the sensitivity and selectivity of particle-based immunoassays via the matrix and shell architecture
  • To develop surface-modified magnetic nanoparticles for diagnostics in vivo
  • To design monodisperse multifunctional microspheres for attaching and separating biomolecules

Content of the research

With the rapid development of biotechnology and nanomedicine, new multifunctional nano- and microparticles with bound ligands are needed for diagnosis and therapy of neurodegenerative diseases, cancer and therapy with cells. The aim fot he project is to design biocompatible particles, optimize their morphology, size, size distribution, charge, and surface, which is decorated with functional groups to ensure colloidal stability in biological fluids, high diagnostics eficiency or simplifaction and efectivity enhancement of biotechnological processes. Particles will be designed also in order to respond to outer magnetic or electromagnetic fields.

Different tailor-made surface modified nano- and microparticles are available for those partners, who are interested.

Otto Wichterle Centre of Polymer Materials and Technologies - CPMTOW

Centre of Biomedicinal Polymers - CBMP

Centre of Polymer Sensors - CPS

Polymers for Power Engineering - Energolab


Institute of Macromolecular Chemistry AS CR
Heyrovského nám. 2
162 06 Prague 6
Czech Republic
tel:+420 296 809 111
fax:+420 296 809 410

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