News archive

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Direct comparison of antifouling properties of poly(2-oxazoline)s and poly(2-oxazine)s

Comparison of the antifouling properties of poly(2-oxazoline) and poly(2-oxazine) polymer brushes, emerging alternatives to PEG, was published in Macromolecular Rapid Communications.

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New copolymers for the membrane protein isolation

Within an international collaboration, IMC scientists developed new, low pH- and Mg²⁺ ions-tolerant copolymers aimed at the isolation and study of membrane proteins.

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Amphiphilic (di-)gradient copoly(2-oxazoline)s are potent amyloid fibril formation inhibitors

Gradient copolymers of hydrophilic and hydrophobic 2-oxazolines effectively inhibit amyloid fibril formation in a concentration-dependent manner, offering promise for treating amyloidoses.

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Control of biocomposites performance using chitin nanoparticles

In Polymers was published a study highlighting effect of amines on surface of chitin nanowhiskers on performance of polycaprolactone/polylactide biocomposites.

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Tuning of morphological and antibacterial properties of PEDOT by methyl violet

Within the national collaboration of IMC-UTB, conducting spherical PEDOT with improved antibacterial properties was prepared and possess diverse spectrum of applications, including optical sensors and medical devices.

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Hyaluronic acid grafted with Ceramide NP for treatment of skin diseases

An article describing the synthesis of Ceramide NP grafted to hyaluronan, a promising molecule for the treatment of inflammatory skin diseases, was published in Carbohydrate polymers.

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A new method of nanoparticle surface modification for diagnostic applications

Team Polymer and Colloidal Immunotherapeutics developed an efficient method for anchoring synthetic polymers to the surface of magnetic nanoparticles. The effectiveness of this surface treatment was subsequently assessed in vivo in collaboration with CAPI team from the 1st Faculty of Medicine.

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Homogeneous ion-exchange membranes for hydrogen production by alkaline water electrolysis

In the framework of the European project NEWELY, the scientific team of IMC and UCT has developed homogeneous ion-exchange membranes with low surface resistance for highly efficient membrane-based alkaline electrolysis of water. The project was awarded the "Best Innovation Award 2022“ of the Clean Hydrogen Partnership at the European Hydrogen Week 2022 - "The secret to success is in the membrane".

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Anti-cancer micellar delivery system with ultrasound-triggered release of the active ingredient

A Czech-French research team has developed an anti-tumor micellar drug delivery system with ultrasound-triggered drug release and successfully tested it in a mousebrain tumor - glioma model. The biodistribution of the system within the organism and its accumulation in tumor can be monitored in real time as a direct feedback by PET or fluorescence.

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Polymer Nanoprobes for Fluorescence-Guided Surgery of Malignant Head-and-Neck Tumors and Metastases

Scientists from the IMC prepared fluorescent polymer probes designed for fluorescent guided surgery, which can light up tumors and more accurately showed tumor borders for easier resection of the whole tumor.

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Polypyrrole Aerogels: Efficient Adsorbents of Cr(VI) Ions from Aqueous Solutions

Scientist from the IMC developed a novel polypyrrole-based adsorbent of Cr(VI) ions with good handling properties for water purifications.

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Influence of coating of upconverting nanoparticles on their degradation and cytotoxicity

IMC scientists designed two-color optical contrast agent with reduced degradability under physiological conditions that is suitable for in vitro and in vivo imaging.

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Study of changes in illumination intensity in the kinetics of the singlet oxygen

As part of the Czech-German-Japanese collaboration, scientists from the IMC participated in the study of changes in illumination intensity in the kinetics of the singlet oxygen signal and photosensitizer phosphorescence in vivo, using time-resolved optical detection in the NIR.

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Hybrid Layers of Donor-Acceptor Copolymers with Silver Nanoparticles

In the journal Nanomaterials, an article revealing the influence of electron-donor units on the formation of silver nanoparticles on the surface of thin layers of donor-acceptor copolymers was published.

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Martin Hrubý was appointed professor

He received the title of professor on the proposal of the Scientific Council of Charles University for the field of macromolecular chemistry.

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Eva Randárová received the Otto Wichterle Award

The OW Prize is awarded to selected, exceptionally high-quality young researchers of the CAS under the age of 35.

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Copolymerization modeling for the development of multifunctional copolymers

Within an international collaboration, IMC scientists participated in a study on the modeling of acrylic acid, methyl acrylate, and t-butylacrylamide copolymerization with the aim to optimize the industrial synthesis of multifunctional copolymers used in personal care products.

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Role of Membrane Features on the Permeability Behavior of Polymersomes

Within the international cooperation of IMC-UFABC, a paper focused on the influence of the permeability of polymersomes membranes on the release of encapsulated drug was published in Biomacromolecules.

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pH-responsive micelles and polymersomes obtained by microwave-assisted RAFT-PISA method

In ACS OMEGA, IMC researches presented a versatile platform for the synthesis of pH-responsive diblock copolymer (PHPMA-b-PDPA) micelles and vesicles (polymersomes) obtained via microwave-assisted RAFT-PISA which may attract considerable attention in the drug-delivery field.

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Polyaniline/metal-organic framework composites: Effect of framework functionalization

Journal ACS Applied Materials & Interfaces published a paper about influence of Zr-based metal-organic framework structure on properties of its composites with polyaniline.

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Conductive mechanisms in cement/CNT composites explored for future geopolymer studies.

First step of future investigations on dielectric properties of geopolymer for sensing applications in the field of building materials - international collaboration results were published in Materials and Structures.

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Multi-layered nanofibrous mats for local delivery of anticancer agent topotecan

The journal Pharmaceutics published a paper on nanofibrous drug carriers with prolonged release and biological activity against cancer cells with potential for local treatment of e.g. intraocular tumor retinoblastoma.

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Rose Bengal-conjugated hexagonal upconverting nanoparticles producing reactive singlet oxygen

IMC scientists designed new Rose Bengal-conjugated and PEG-coated hexagonal upconverting nanoparticles to kill tumor cells by photodynamic therapy.

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In vivo Post-Grafting Safety of Reprogrammed Human iPSC-Derived Neuronal Precursors

The journal Cell Transplantation has published results of in-vivo study of the survival, differentiation, and safety/tumorigenicity of reprogrammed human induced pluripotent stem cells-derived neuronal precursors for treatment of neurodegenerative diseases.

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Poly(glycidyl methacrylate)-based polymers for automotive coatings

In research sponsored by the U.S. company Axalta Coating Systems, IMC scientists described the synthesis of well-defined low-molecular weight (co)polymers of glycidyl methacrylate applicable in the formulation of automotive coating mixtures.

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Newly developed gel polymer electrolytes based on crosslinked poly (2-oxazolines)

Journal Solid State Ionics published work on the development of electrochemically, mechanically and thermally stable, efficient and versatile “green” gel polymer electrolytes for lithium-ion batteries based on cross-linked 2-polyoxazolines.

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Magnetic inorganic-organic-polymer nanoparticles for treatment of neurodegenerative diseases.

Researchers from IMC substantially contributed to the characterization of nanoparticles, which exhibit promising therapeutic properties for the treatment of Hungtington disease - a neurodegenerative disease of brain.

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Smart PLA-b-PTEGMA copolymers: synthesis, temperature behavior, and paclitaxel release.

Interesting research published in Pharmaceutics manufactured novel amphiphilic, biocompatible and thermo-responsive PLA-b-PTEGMA copolymers synthesized via one-pot controlled RAFT-ROP polymerizations with fine-tuneable LCST. NPs prepared from them encapsulated and release paclitaxel by temperature-triggered drug release mechanism in relevant pathophysiological temperatures.

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Electron beam radiografting of nonbiofouling polymer hydrogel layers

IMC scientists developed a method using electron beam irradiation to create nonbiofouling hydrogel coatings on implantable materials, improving biocompatibility and in vivo performance. Crosslinkable double bond concentration in the copolymer is crucial for stability and uniformity of the formed hydrogel layer.

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Professor Pavel Kratochvíl passed away

We are deeply saddened to announce that on April 7th 2023, the physical chemist and leading expert in polymer chemistry Prof. Ing. Pavel Kratochvíl, DrSc. passed away.

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Indentation- vs. Macromechanical characterization of nanocomposites with monodisperse rigid filler

A study was published in Materials, comparing the above characterizations on hydrogen-bond-rich rubbery elasto-plastic nanocomposites containing a monodisperse spherical rigid filler.

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Synthesis and anti-fouling properties of zwitterionic poly(L-glutamic acid)

The journal Macromolecular Research published a study describing the synthesis and characterization of biocompatible and biodegradable polymers based on poly(L-glutamic acid) bearing zwitterionic groups. The developed materials can be used in tissue engineering.

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Efficient complexation of animal venom melittin with polymer carriers

Cationic amphiphilic animal venoms like melittin can be complexed with polyanionic nanoparticles to form potential therapeutic agents with high efficacy. Article was published in the European Polymer Journal.

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Phosphorus-Containing Polymers as Sensitive Biocompatible Probes for 31P Magnetic Resonance

The journal Molecules has published a study describing the synthesis and characterization of biocompatible phosphorus-containing polymers that can be used as highly sensitive probes in 31P MRI imaging of internal body structures.

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The effect of a protective coating of NaYF4:Yb,Er nanoparticles on biomedical properties

Upconverting NaYF4:Yb,Er nanoparticles modified by bisphosphonate-terminated poly(ethylene glycol) and Rose Bengal produced reactive oxygen species potentially to kill cancer cells.

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Prague Meeting on Tumor Therapy and Imaging

Between 19 and 21 March 2023, IMC has organized an international conference focused on the presentation of the recent results and sharing of experience in the field of cancer treatment and diagnostics.

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Polymer brushes based on N-methacryloxysuccinimide as platform for versatile post-polymerization modification

A new method for the synthesis of N-methacryloxysuccinimide based polymer brushes via surface-initiated atom-transfer radical polymerization and subsequent post-polymerization modification was presented in the journal Progress in Organic Coatings.

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Plasmonic Ag/Cu/PEG Nanofluids Prepared when Solids Meet Liquid in the Gas Phase

Journal Nanoscale Advances published an article describing an excellent platform for fundamental research on non-aqueous nanofluids, with metal-polymer and metal-metal interactions unperturbed by the presence of solvents or chemical residuals.

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A novel, temperature-independent polymer system for cell cultivation and non-destructive harvesting

An international team of scientists has succeeded in developing a new and universal, temperature-independent system for non-destructive cell harvesting. By biofunctionalization of polymer brushes, surfaces enabling adhesion, cultivation and subsequent on-demand harvesting of fibroblasts were prepared.

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Polymer-Antimicrobial Peptide Constructs with Tailored Drug-Release Behavior

Journal Pharmaceutics published an article presenting the design, synthesis, and preliminary biological evaluation of polymer-antibacterial peptide constructs.

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Polypyrrole-BariumFerriteMagnetic Cryogels for Water Purification

Researchers from the IMC synthesized efficient adsorbents for water purification due to their enhanced adsorption performance and the possibility of facilitated separation from solution by a magnetic field.

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New technology will make immunoassays faster, easier and cheaper

Scientists, in collaboration with industrial developers, have developed a technology that can prepare a fully synthetic polymer and make it significantly easier and cheaper to carry out analyses aimed at proving the presence of a pathogen or a specific antibody in the body.

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pH-Responsive giant polymeric vesicles prepared via polydimethylsiloxane (PDMS) microfluidics

An international team of researchers developed pH-responsive giant polymer vesicles.

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Controlled radical polymerization of 2-hydroxyethyl methacrylate in a non-polar solvent

Scientists from IMC described how 2-hydroxyethyl methacrylate (HEMA) can be polymerized rapidly in a controlled fashion generating high MW poly(HEMA) and providing direct access to amphiphilic copolymers.

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Dye labeling for optical imaging biases drug carriers' biodistribution and tumor uptake

Recently published study compares the biodistribution and tumor accumulation of four fluorescently labeled polymer conjugates and low molecular weight fluorescent labels in tumor cells.

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A new method of acid assisted polymerization

Journal of Materials Chemistry B has published a study presenting a new synthetic method for the fabrication of the PANI sensing layer for the potentiometric detection of iron.

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PhD projects

Registrations are now closed, applications are being evaluated and selected candidates will be invited for a personal interview.

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Wiley Encyklopedia: Micromechanical properties of polymers

Miroslav Šlouf, the head of the department of Polymer Morphology has written a new chapter for the 4th edition of the Encyklopedia of Polymer Science and Technology (Wiley).

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Macroporous conducting materials for supercapacitor applications

Journal Materials Chemistry and Physics has published a study on macroporous conducting materials for supercapacitor applications.

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Welcome Meeting: UNESCO/IUPAC Postgradual Course in Polymer Science

We have officially started the 27th run of the Postgraduate Course in Polymer Science, which we organize under the auspices of the Czech Academy of Sciences, UNESCO and IUPAC/International Union for Pure and Applied Chemistry.

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Polymers for energy accumulation systems

Researchers from the IMC described a new approach to using Al-ions for the accumulation of energy in an organic polymer–polyaniline (PANI).

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Gene therapy for patients with spinal cord injuries

An international team of scientists is continuing research on gene therapy for patients suffering from neuropathy. The results of the new study have been published in the journal Molecular Therapy.

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Director of IMC got an honorary doctorate degree in Lyon

Jiří Kotek, director of IMC, received an honorary academic degree from INSA Lyon.

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Nanoparticles for radiosensitization therapy of cancer

Scientists from the IMC have conducted research on self-assembled nanoparticles for radiotherapy oncological diseases.

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National Institute for Cancer Research

Czech researchers would like to improve the diagnosis and treatment of cancer at the newly established National Institute for Cancer Research. The institute will connect 71 research teams from 11 centres including researchers from the IMC.

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Polymeric systems for the treatment of metastatic tumors

A new study appeared as the cover story of the August issue of the journal Nanomedicine: Nanotechnology, Biology, and Medicine.

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New publication in Biomacromolecules

Researchers from the Czech Academy of Sciences have now studied in detail the anti-tumor support of a derivative of Ritonavir.

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Polymeric sensor for the detection of iron ions

The collaboration of researchers from the IMC has brought another success: a new publication in journal Biosensors.

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Nanogels for suppressing the effect of pro-inflammatory enzymes

Team of scientists from the IMC is working on the development of a nanogel depot based on synthetic polyamino acids.

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Open Days 2022

We cordially invite you to our Institute for Open Days from November 2–3, 2022.
We are looking forward to meeting every fan of polymer sciences!

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Polymers 2022

The beginning of October belongs to the conference Polymery 2022 which is organized by the Institute of Macromolecular Chemistry CAS.

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Hydrogel implant for the treatment of retinoblastoma

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Progress in development of polymer organic solar cells

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“Smart” stimuli-responsive polymeric systems for sensing applications

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Polymer nanoparticles for the diagnosis of cardiovascular diseases

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Review on emerging polymer therapeutics of iron and copper overload

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84^th Prague Meeting on Macromolecules

The 84^th Prague Meeting on Macromolecules "Frontiers of Polymer Colloids – From Synthesis to Macro-Scale and Nano-Scale Applications" took place at the Institute of Macromolecular Chemistry CAS.

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Polymer probes for phosphor magnetic resonance imaging

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Nanoparticles from the IMC could help to better diagnose serious diseases

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Nature Energy: organic solar cells made from non-toxic solvents

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We support Ukraine

IMC stand in solidarity with the people of Ukraine.

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PhD at IMC 2022/2023 – Discover new research opportunities

We are looking for new PhD students interested in advanced material and biomedical research.

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Development of an antibody mimetic using iBody

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Improvement of a new scanning electron microscopy method

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Development of hydrogel implants for the treatment of eye tumors

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Research of more durable composite material

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The UNESCO/IUPAC Postgraduate Course celebrates 26^th run

We launched the 26^th run of the international Postgraduate Course in Polymer Science.

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The new paper about ongoing research of 3D bioprinting

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Environmentally-friendly microwave synthesis of biodegradable packaging films

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Drug-free macromolecular therapeutics

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The Prize for pharmacy goes to IMC

Dr. Jiří Trousil from the Department of Biological Models received the Prize for Pharmacy.

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Synthesis of a ritonavir derivative and its attachment to a polymeric carrier

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Bioresource Technology: A new type of polymer membranes from the IMC

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Zuzana Morávková and Rafał Konefał received the Otto Wichterle Award

Congratulations to Dr. Zuzana Morávková from the Department of Vibrational Spectroscopy and Rafał Łukasz Konefał from the Department of NMR Spectroscopy for receiving the Otto Wichterle Award!

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pH-responsive polymersome-mediated delivery of doxorubicin

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Synthesis and structural characterization of bio-based polyurethanes

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Research of polymer electrolytes for lithium-ion batteries

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A new method of scanning electron microscopy

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Development and design of perovskite LEDs

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Biodegradable nanocarriers for drug delivery

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A new paper from the Department of Biomedical Polymers in the journal Pharmaceutics

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Biomacromolecules: Biomimetic hydrogels for tissue engineering

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A new generation of medicinal products derived from HemaGel

Scientists from the IMC CAS have managed to develop a new generation of medicinal products derived from the original product used to accelerate healing of injuries called HemaGel.

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EPF Inter-Congress Workshop

We shall organise a one-day on-line EPF Inter-Congress Workshop during the period at the end of June in 2021.

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Dr. Ing. Jiří Kotek is appointed director of the IMC

We would like to inform you that Dr. Ing. Jiří Kotek has been appointed director of the IMC CAS, v. v. i. for the second five-year term beginning on April 1, 2021.

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Research on the enhanced ordering of block copolymer thin films

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Review of nanotherapeutics based on HPMA copolymers

Comprehensive review article describing the issue of HPMA polymer systems associated with the use of the so-called EPR effect in the treatment of solid tumors.

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Light-converting lanthanide nanoparticles for the detection of human albumin

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A new type of ionically-conductive material for the production of safer batteries

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Polymer nanotherapeutics from IMC in the Journal of Controlled Release

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Success of the Department of NMR spectroscopy in Inorganic Chemistry

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Biomacromolecules: Polymeric nanosystems for effective inhibition of galectin-3

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PhD projects – Call for Applications 2021/2022

We are looking for new PhD students who are interested in advanced material and biomedical research, deepening their knowledge of macromolecular science.
Register by 8 March 2021.

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The Czech Academy of Sciences and Charles University have agreed on further cooperation within the BIOCEV center

Two of the largest research and education institutions will continue collaborating in the BIOCEV.

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Professor Karel Dušek, Emeritus Principal Scientist of IMC, passed away

The management of the Institute of Macromolecular Chemistry, Czech Academy of Sciences announces with deep sorrow that on 30 October 2020, prof. Ing. Karel Dušek, DrSc. passed away at the age of 90.

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License for use of iBodies® to measure free testosterone in blood

The Institute of Macromolecular Chemistry, CAS, the Institute of Organic Chemistry and Biochemistry, CAS and Charles University have signed a licensing agreement with the company Immunotech for the use of iBodies®, a joint technology for measuring free testosterone in blood

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Oxygenerator succeeded in Hack the Crisis

The team of scientists of the Polymer membranes dept won the fourth place from all 206 projects registered in the Hack the Crisis contest organized by the CzechInvest agency.

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Oxygenerator with membrane – registered on covid19.cz

Oxygenerator invented by the IMC scientists in cooperation with the Czech membrane R&D company MemBrain differs from other oxygenerators by utilization of hollow fibre membrane, which filters 100% of all viruses and increases oxygen content up to 45% (or more).
We welcome any cooperation for production.

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Czech presidency of the European Polymer Federation for 2020 - 2021

The elected president for the years 2020 – 2021 is Dr. Jiri Kotek, director of the Institute of Macromolecular Chemistry CAS and representative of the Czech Chemical Society.

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60 years of the Institute of Macromolecular Chemistry

We celebrated 60 years of foundation of the Institute by Professor Otto Wichterle.

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European Polymer Congress 2022

The Institute of Macromolecular Chemistry of the CAS within the European Polymer Federation organizes the conference. It will be held 26 June – 1 July in Prague.