News archive

Ostatní

A new strategy to determine whether nanotherapy will be effective for a patient

Scientists from the IMC participated in the development of a strategy to find out whether the treatment with advanced forms of nanomedicine will be of significant benefit to the patient, or will remain without effect.

Ostatní

Polyacrylamide-cellulose hydrogel derived carbon materials for high-performance supercapacitors

The journal ACS Applied Energy Materials published a collaborative study on ultrahigh surface area hierarchically porous carbon materials and their potential use as high-performance supercapacitors.

Ostatní

RGD-coated polymeric microbubbles enable drug delivery across the blood-brain barrier

We discovered that sonopermeation with microbubles enhances delivery across the blood-brain barrier of both nanocarriers and free drugs.

Ostatní

Advanced polymeric vectors for the treatment of site-specific rheumatic musculoskeletal diseases

Researchers from ÚMCH, together with colleagues from BFU and the Institute of Rheumatology, developed polymer vectors with optimized drug activation for the treatment of rheumatic diseases.

Ostatní

Effect of Polymer Concentration on the Morphology of the PHPMAA-g-PLA Graft Copolymer Nanoparticles Produced by Microfluidics Nanoprecipitation

Researchers from IMC have demonstrated the feasibility of preparing PHPMAA-g-PLA polymer nanoparticles with various morphologies using microfluidic channels.

Ostatní

Polymeric adjuvants designed to increase the efficiency of polymer nanosystems in tumor therapy

We have developed a polymer nanosystem that can increase the uptake of other therapeutic nanosystems in tumor tissue, thereby significantly increasing their therapeutic efficacy.

Ostatní

Nano-FTIR spectroscopy of surface confluent polydopamine films

Nanoscale infrared characterization of polydopamine layers was published in Colloids and Surfaces B: Biointerfaces.

Ostatní

Electrodestruction of bacterial biofilm on polymer layers

Scientists from the IMC have developed polymer layers capable of significantly increasing the efficiency of electrosterilization of surfaces with bacterial biofilm.

Ostatní

Highly effective synthetic polymer-based blockers of non-specific interactions

Researchers from IMC have developed highly effective synthetic polymer blockers of non-specific interactions, which make it possible to replace currently used proteins of animal origin.

Ostatní

Polymersome nanovaccines enhance antitumor immunity with co‑delivered antigens and adjuvants

IMC and Radboud University Medical Center developed polymersome nanovaccines boosting antitumor immunity by co-delivering antigens and adjuvants to dendritic cells.

Ostatní

Aluminosilicate networks as Lewis acid catalysts: Synthesis and characterization

The journal Inorganic Chemistry has published a comprehensive study that reveals the mechanism of formation of catalytically active aluminosilicate networks and provides a detailed insight into the structure of the resulting Lewis acid centers.

Ostatní

Cancer cell membrane targeting with tailored highly defined polymers

Scientists from the IMC CAS developed in collaboration with the IOCB CAS highly defined "octopus" peptoid polymers targeting cancer cell membranes.

Ostatní

Degradation of polyolefins with phenolic stabilizers subjected to ionizing or non-ionizing radiation

IMC researchers showed that phenolic stabilizes (such as vitamin E) exhibit both antioxidant and prooxidant properties, depending on the irradiation type.

Ostatní

Sustainable aerogels made of poly (itaconic acid) for wastewater remediation

International Journal of Biological Macromolecules recently published the use of aerogels for dyes adsorption. These aerogels are considered a promising adsorbent material for wastewater remediation.

Ostatní

Non-conventional light-mediated therapy with ferrocene-based polymer micelles

Scientists from the IMC developed non-conventional light-triggered approach to killing cancer cells using ferrocene-containing polymer micelles.

Ostatní

Tannic acid-modified magnetic nanoparticles reduce oxidative stress in liver

Magnetic iron oxide nanoparticles modified with tannic acid and N-acetylcysteine-chitosan conjugate reduce oxidative stress in liver of prediabetic rats.

Ostatní

38 nm biodegradable poly[N-(2-hydroxypropyl) methacrylamide] nanogels by dispersion polymerization

The scientists from the IMC developed the conditions of dispersion polymerization for the preparation of 38 nm core shell biodegradable, hydrophilic and reactive nanogels.

Ostatní

Biobased ultralow-density polyurethane foams with enhanced recyclability

We have prepared ultra-light polyurethane foams from renewable feedstock showing increased recyclability, which contribute to circular economy and solving plastic waste concerns.

Ostatní

Novel natural-based alginate-pectin networks dually crosslinked with Ca2+/Zn2+ ions for the delivery of lipophilic phytotherapeutics

The close collaboration of the IMC CAS, MUNI Pharm and VRI resulted in the design of advanced hybrid alginate-pectin networks, proposed as the long-term site-specific treatment of intestinal inflammation.

Ostatní

Mechanically strong and extensible monolithic hydrogels with rapid response to temperature change

Strong and tough monolithic non-porous hydrogels have been developed: poly(N-isopropylacrylamide) interlaced with hydroxypropylmethylcellulose. Some exhibited an exceptionally rapid response to temperature changes.