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From 4th June 2012 to 15th June 2012 in the Institute gallery of IMC AS CR, an exhibition P.O.L. E. art group:reconstruction of one exhibition from 1972 -1989 takes place
76 PMM Conference Polymers in Medicine is to be held in Prague on 1 - 5 July 2012. Career in Polymers 2012 workshop to take place before the conference.
MoDeSt 2012 conference is to be held in Prague from 2 to 6 September 2012
| Supervisor (Consultant) | Jan Dohnálek, PhD Consultant Dr.Tereza Skalova, PhD |
|---|---|
| Topic | 3D structure studies of natural killer cell receptors. |
| Annotation | Mammalian immune system relies on a number of receptors recognizing virus infected or cancer cells. A special type of lymphocytes recognizes such cells via a row of surface receptors and upon positive identification of an enemy a cascade of events leading to lysis of the contacted cell is initiated. These natural killer cells can avoid cells of their own organism but attack effectively for instance virus-infected cells. The molecular mechanism of this recognition has not been fully understood yet. We elucidate structure and function of these surface receptors mostly by means of X-ray diffraction analysis. The work includes protein purification, characterisation, and crystallization, diffraction screening, data collection at synchrotron radiation sources, structure solution and interpretation. |
Center BIOPOL
Center BIOpolymer POstdoctoral Laboratory and educational center arises with finantial support from EU funds, operational programme Education for Competitiveness
Institute of Macromolecular Chemistry AS CR, v.v.i.
Heyrovského nám. 2
CZ-162 06 Praha 6
Czech Republic
phone:+420 296 809 111
fax:+420 296 809 410
