Supervisor
(Consultant)
RNDr.Jan Svoboda, Ph.D.
TopicStudy of the initial self-assembly processes during the formation of biomimetic anchor layers
AnnotationBioinspired chemistries based on phenols, polyphenols, catechol amines, etc. have been extensively used as substrate independent modification approaches for the creation of surface confluent anchor layers in various applications. Though widely used, the actual composition and initial steps of the anchor layer formation have been rarely accessed. The main objective of the thesis is to develop methods for the detailed investigation of the initial steps of self-assembly of different biomimetic anchor layers based on epigallocatechin gallate, epicatechin gallate (ECG), epigallocatechin, tannic acid, dopamine, and their synthetic counterparts. Spectroscopic ellipsometry (SE) combined with quartz crystal microbalance (QCMD) and surface plasmon resonance (SPR) spectroscopy measurements will be used for the in situ monitoring of the formation of the bioinspired layers. X-ray photoelectron spectroscopy (XPS) and far field grazing angle attenuated total reflection FTIR will be used to probe the overall macroscopic covalent structure of the resulting surfaces. Near field methods such as nano-FTIR and sSNOM will be used to determine the covalent structure on the microscale. The changes in surface topography, morphology and surface potential of the modified substrates will be investigated by SPM techniques, such as atomic force microscopy, scanning electron microscopy and Kelvin probe force microscopy. Single molecule force spectroscopy will be used to probe the interactions between the anchor precursors and different surfaces. "

BIOpolymer POstdoctoral Laboratory and educational center - BIOPOL

Otto Wichterle Centre of Polymer Materials and Technologies - CPMTOW

Centre of Biomedicinal Polymers - CBMP

Centre of Polymer Sensors - CPS

Polymers for Power Engineering - Energolab


 

Institute of Macromolecular Chemistry AS CR, v.v.i.
Heyrovského nám. 2
CZ-162 06 Praha 6
Czech Republic
phone:+420 296 809 111
fax:+420 296 809 410

Strategie 21