Supervisor
(Consultant)
Assoc. Prof.Miroslav Šlouf, PhD.
TopicBiodegradable polymer systems for medical applications
AnnotationBiodegradable and biocompatible polymer systems show numerous applications in both human and veterinary medicine. We have recently developed two series of multiphase polymer systems based on thermoplasticized starch (TPS), polycaprolactone (PCL), poly(lactic acid) (PLA), titanium dioxide based nanoparticles (TiX) and antibiotics (ATB). Morphology and properties of these systems can be adjusted by their composition and targeted phase structure modification during the processing. TPS/PCL/TiX/ATB systems can be employed in treatment of strong local infections such as osteomyelitis, while PLA/PCL/TiX seem to be very suitable for bone tissue engineering. The dissertation would comprise preparation of the above systems (by melt mixing), optimization of their phase structure (targeted modification of preparation conditions), characterization of their morphology (electron microscopy) and properties (toughness, microindentation etc.), and participation in medical tests in collaboration with FN Motol (treatment of local infects, biodegradability).

BIOpolymer POstdoctoral Laboratory and educational center - BIOPOL

Otto Wichterle Centre of Polymer Materials and Technologies - CPMTOW

Centre of Biomedicinal Polymers - CBMP

Centre of Polymer Sensors - CPS

Polymers for Power Engineering - Energolab


 

Institute of Macromolecular Chemistry AS CR, v.v.i.
Heyrovského nám. 2
CZ-162 06 Praha 6
Czech Republic
phone:+420 296 809 111
fax:+420 296 809 410

Strategie 21