Assoc. Prof. Miroslav Šlouf, PhD.
TopicBiodegradable polymer systems for medical applications
AnnotationBiodegradable and biocompatible polymer systems show numerous applications in both human and veterinary medicine. We have recently developed two series of multiphase polymer systems based on thermoplasticized starch (TPS), polycaprolactone (PCL), poly(lactic acid) (PLA), titanium dioxide based nanoparticles (TiX) and antibiotics (ATB). Morphology and properties of these systems can be adjusted by their composition and targeted phase structure modification during the processing. TPS/PCL/TiX/ATB systems can be employed in treatment of strong local infections such as osteomyelitis, while PLA/PCL/TiX seem to be very suitable for bone tissue engineering. The dissertation would comprise preparation of the above systems (by melt mixing), optimization of their phase structure (targeted modification of preparation conditions), characterization of their morphology (electron microscopy) and properties (toughness, microindentation etc.), and participation in medical tests in collaboration with FN Motol (treatment of local infects, biodegradability).
UniversitiesVysoká škola chemicko technologická v Praze, Přírodovědecká fakulta UK, Matematicko-fyzikální fakulta UK, Technická univerzita Liberec, Přírodovědecká fakulta Univerzity Palackého Olomouc, Universita Tomáše Bati Zlín

Otto Wichterle Centre of Polymer Materials and Technologies - CPMTOW

Centre of Biomedicinal Polymers - CBMP

Centre of Polymer Sensors - CPS

Polymers for Power Engineering - Energolab


Institute of Macromolecular Chemistry AS CR
Heyrovského nám. 2
162 06 Prague 6
Czech Republic
tel:+420 296 809 111
fax:+420 296 809 410

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