RadioLAB Even though radionuclides have been long and successfully applied in medicine and natural sciences, they bring a new perspective to biomedicine in combination with polymers. Radioisotopes are used for in vivo molecular display, specifically by scintigraphic methods (e.g. planar scintigraphy, SPECT) or tomographic methods (PET). Especially promising are the diagnostic systems that combining advantages of different display modalities, e.g. the high sensitivity of scintigraphy and high resolution of magnetic resonance (MRI) or fluorescence displaying. Last not least, radiodiagnostics can be effectively combined with therapy under theranostics systems, which allow for a “custom-made” therapy, so progressive and sought-for nowadays, since it provides a reliable feedback by showing the biodistribution of a drug before another dose is given.
Radioanalytical methods and radioisotope tracing are irreplaceable in biomedical research of implants used in human medicine, being uncomplicated and universally applicable but also, above all, being characteristic with a high concentration sensitivity that is virtually unattainable by any other method used and plays a crucial role in developing new biomaterials, e.g. those used in tissue engineering.
Polymers can contribute to constructing advanced biomedical systems applicable in the aforementioned fields, as well as in many others, for instance in developing well-defined implants for tissue engineering or magnetic nanoparticles with biocompatible surface and radioactive marker.
Currently, the IMMC’s radionuclide laboratory is one of Europe’s few institutions where experts can study and develop polymers for medical applications using radionuclide marking.
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